In the multiple stepwise regression analysis, IDL-C as well as body mass index (BMI) significantly correlated with both F-score and S-score in both the total subjects and the subjects without drug therapy.
Results: Non-HDL-C, IDL-C, and VLDL-C significantly correlated with F-score and S-score. This study enrolled 476 men, aged mean 51 years and free of CHD and stroke. Methods: The cholesterol levels of lipoproteins, including triglyceride (TG)-rich lipoproteins (IDL and VLDL), were measured by an anion exchange high-performance liquid chromatography (AEX-HPLC). We reported the relevance of IDL-C to Framingham risk score (F-score), but the present study addressed the relevance of IDL-C to Suita score (S-score), a risk score for coronary heart disease (CHD) developed for the Japanese individuals in addition to F-score. 6Department of Health Science, Laboratory Science, Saitama Prefectural University, Saitama, Japanīackground: Not only low-density lipoprotein (LDL) cholesterol but also non-high-density lipoprotein cholesterol (non-HDL-C), very low-density lipoprotein (VLDL) cholesterol (VLDL-C), and intermediate-density lipoprotein (IDL) cholesterol (IDL-C) are reported to be significant risk markers for coronary heart disease (CHD).5Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women's University, Tokyo, Japan.4Bioscience Division, TOSOH Corporation, Kanagawa, Japan.3Nihonbashi Sakura Clinic, Tokyo, Japan.2Internal Medicine of Metabolism and Nutrition, The Jikei University Graduate School of Medicine, Tokyo, Japan.1Department of Laboratory Medicine, The Jikei University Kashiwa Hospital, Kashiwa, Japan.Hiroshi Yoshida 1,2 *, Kumie Ito 3, Daisuke Manita 4, Ryo Sato 1, Chika Hiraishi 2, Sadako Matsui 5 and Yuji Hirowatari 6 *
0 kommentar(er)
